A recent study published in the journal BMJ Evidence Based Medicine suggests that individuals with unhealthy lifestyle habits and genetic predispositions are twice as likely to die prematurely compared to those with good habits and genes. Lifestyle factors such as not smoking, regular physical activity, adequate sleep, and a healthy diet were found to have the greatest impact on longevity. The research indicated that individuals who adopt healthy lifestyle habits can offset their genetic risk for premature death by over 60%. By quitting smoking, moderating alcohol consumption, engaging in physical activity, getting enough sleep, and maintaining a healthy diet, individuals can potentially extend their lifespan by nearly 5.5 years starting at age 40.
Genes play a significant role in determining one’s risk of developing diseases such as cancer, heart disease, and diabetes, among others. However, this study revealed that lifestyle choices can have a profound impact on an individual’s overall lifespan. By focusing on factors within their control like nutrition, physical activity, smoking, and sleep, individuals can shape their future health outcomes. The study emphasized the importance of healthy lifestyle habits in mitigating the effects of genetic risk factors on lifespan reduction.
The research, which involved 353,742 adults recruited to the UK Biobank between 2006 and 2010, tracked participants’ health outcomes until 2021. Utilizing a polygenic risk score tool, the researchers assessed participants’ genetic risk of living a longer or shorter life. They found that individuals with a genetic predisposition to early death were 21% more likely to die during the study period, regardless of their lifestyle choices. Conversely, those with an unhealthy lifestyle were 78% more likely to die early compared to those with healthy habits. Notably, individuals with both unhealthy lifestyle habits and genetic predispositions had double the risk of premature death compared to those with good health habits and favorable genetic profiles.
A separate study published in The Lancet Healthy Longevity by the Chinese Center for Disease Control and Prevention supported these findings, emphasizing the positive impact of adopting a healthy lifestyle on mortality risk and life expectancy. Researchers at San Diego State University also conducted a study focusing on genes, lifestyle, and longevity among older women in the United States, highlighting the importance of engaging in positive lifestyle behaviors such as regular exercise and limiting sedentary behavior. Despite genetic predispositions, individuals can still extend their lifespan by making healthy choices.
Healthcare practitioners believe that this information can empower individuals to take control of their health and make sustainable changes that contribute to long-term well-being. Rather than relying solely on genetics, individuals are encouraged to adopt healthy lifestyle habits that align with their preferences and schedules for improved long-term health outcomes. The key message is that genetics may load the gun, but lifestyle choices ultimately pull the trigger in determining an individual’s lifespan and overall health. By making informed choices and prioritizing health-promoting behaviors, individuals can positively impact their longevity and well-being.